Tucked away in the charming neighborhood of Northwood, this remarkable home stands as the largest in the area, boasting an impressive 2,334 heated square feet on a serene 0.51 acre lot along Possum Creek. Designed with a thoughtful split floor plan, the layout ensures a perfect blend of privacy and comfort. The expansive living area features a cozy wood burning fireplace, flowing seamlessly into a large open kitchen with clean, practical tiling, stainless steel appliances, a picturesque backyard view with convenient access to a two car garage, offering ample storage space along with a dedicated laundry area. A true retreat, the master suite offers a wealth of space and comfort. Significant updates include modernized guest bathrooms and plumbing (upstairs and downstairs), stylish new flooring in two bedrooms, and a HVAC system (2021). Venture downstairs to discover a finished mother in law suite this versatile space doubles as an Air B&B, man cave, or hobby room, complete with a private entrance. Enjoy your morning coffee or evening cookout in the privacy of your fenced in backyard with a spacious deck. Surrounded by Florida's natural beauty, you'll immerse yourself in the sound of bird songs, while marveling at wildlife passing through and enjoying the lovely creek just beyond the woods. Ideally located just minutes from I 75, this residence provides quick access to UF, Santa Fe, Shands, and North Florida hospitals, along with an array of nearby shopping, dining, parks, and schools, all while preserving the tranquil charm of suburban living (without the restrictions of a HOA!).